Ernesto Staroswiecki1,2, Kristin Lee Granlund1,2, Marcus Tedrow Alley1, Garry Evan Gold1, Brian Andrew Hargreaves1
1Radiology, Stanford University, Stanford, CA, United States; 2Electrical Engineering, Stanford University, Stanford, CA, United States
Detailed visualization of articular cartilage is a challenge that requires advanced MRI techniques. In order to detect early changes of osteoarthritis, we require contrast mechanisms capable of showing biochemical properties of cartilage like T2-mapping and diffusion-weighted-imaging. Here we study the diffusion sensitivity of the T2 maps of cartilage generated with a DESS sequence, and present a method for generating T2-weighted and diffusion-weighted images, together with T2 maps and relative-ADC maps of cartilage via two sequential DESS acquisitions with different gradient amplitudes.