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Abstract #0838

Sequential Change of Rat Cartilage and Subchondral Bone with Experimental Osteoarthritis Investigated by Quantitative T2* Measurements

Ping-Huei Tsai1, Ming-Chung Chou2, Ming-Huang Lin3, Chien-Yuan Lin3, Hsaio-Wen Chung1, Herng-Sheng Lee4, Guo-Shu Huang2

1Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan; 2Department of Radiology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan; 3Institute of Biomedical Sciences, Academic Sinica, Taipei, Taiwan; 4Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan


Osteoarthritis (OA) is a disease related to the degeneration of cartilage, pathological change of subchondral bone (SB) and so force, which may leads to a series of inflammation and pain responses.