Bhaskaran David Prakash1, Loyola D'Silva1, Kishore Bhakoo1, David Townsend1, S. Sendhil Velan1
1Laboratory of Molecular
We have implemented and validated the LCT-PRESS technique in healthy rat brain. This sequence clearly demonstrates superior resolution and permits reliable detection of several brain metabolites that overlap in conventional techniques. The LCT-PRESS sequence performs this separation due to its incorporation of constant-time evolution, resulting in spin-spin decoupling along the F1 dimension.