Grzegorz Lukasz Chadzynski1, Adriane Groeger2, Uwe Klose3
1Department for Diagnostic and Interventional Neuroradiology, University Hospital Tuebingen, Tuebingen, Baden- Wuerttemberg, Germany; 2Department of Neurodegeneration, Hertie Institute for Clinical Brain Research, Tuebingen, Baden-Wuertemberg, Germany; 3Department for Diagnostic and Interventional Neuroradiology, University Hospital Tuebingen, Tuebingen, Baden-Wuertemberg, Germany
Recent studies showed that the frequency distance between water and NAA measured with 1HMRS may be used for temperature evaluation. We examined regional difference of this distance in the human brain at the level of the lateral ventricles. CSI measurement were performed for 11 healthy volunteers. Spectra were acquired at 3T with PRESS localization without water suppression. We found water to NAA frequency distance to be greater in white than in gray matter with mean difference value of 0.013 ppm. According to the literature this would be approximately equal to 1oC. More reliable results can be obtained after calibration measurements.