Lindsay Cherpak1,2, Kimberly Brewer1,2,
Jodie Gawryluk1,3, Nicole Pelot1,2, Chris Bowen1,4,
Ryan D'Arcy1,3, Steven Beyea1,4
1Institute for Biodiagnostics
(Atlantic), National Research Council of Canada, Halifax, Nova Scotia,
Canada; 2Physics and Atmospheric Science, Dalhousie University,
Halifax, Nova Scotia, Canada; 3Psychology, Dalhousie University,
Halifax, Nova Scotia, Canada; 4Physics and Atmospheric Science,
Radiology and Biomedical Engineering, Dalhousie University, Halifax, Nova
Scotia, Canada
This
study involved a comprehensive evaluation of commonly-used techniques like
EPI and spiral-out, as well as techniques designed to recover signal in SFG
regions using BOLD methods (spiral-in, spiral-in/out, spiral-in/in and ASE
spiral) and non-BOLD methods (FAIR and spin-echo spiral-in/out) at 4.0 T. A
cognitive task used to evaluate temporal lobe epilepsy patients was presented
to elicit activation in the inferior temporal lobe (as well as other brain
regions). Notably, this work allowed us to examine the differing effects that
the contrast and signal recovery mechanisms have on fMRI activation in both
SFG and non-SFG regions.