Salem Boussida1, Amidou Traore2, Jean-Pierre Renou2, Franck Durif3
1INRA, UR370 QuaPA/NMR plateforme, Centre Clermont-Ferrand/Theix, F-63122 Saint Gens Champanelle, France; 2INRA, UR370 QuaPA/NMR plateforme, Centre Clermont-Ferrand/Theix, F-63122 Saint Gens Champanelle, France; 3CHU Clermont-Ferrand, Service de Neurologie, Clermont-Ferrand, F-63001, France.
Combination of blood oxygen level-dependent functional magnetic resonance imaging (BOLD fMRI) and electrical hindpaw stimulation has been used as a standard model to study the somatosensory pathway and brain rehabilitation in rats. In the present study, we examined the feasibility of performing BOLD fMRI experiments on rat to investigate the activity of the basal ganglia (BG)-cortex circuit associated to hindpaw sensitive stimulation. These findings will have relevance in the fMRI studies dealing with physiopathology of neurodegenerative diseases such as Parkinson