Kilian Weiss1, Nicola Martini2, Peter Boesiger1, Sebastian Kozerke1
1Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland; 2Interdepartmental Research Center "E. Piaggio", University of Pisa, Pisa, Italy
Single-voxel proton magnetic resonance spectroscopy has been shown to be a promising tool for assessing creatine and myocardial triglycerides in humans. While spectral information from a single volume is sufficient when alterations with global effects on the heart are studied, a demand for higher and flexible spatial resolution exists when probing local changes. To this end, implementation of fast spectroscopic imaging of the heart is desired. The objective of the current work was to implement and optimize navigator gated and cardiac triggered Echo-Planar Spectroscopic Imaging (EPSI) for assessment of triglyceride and creatine content in the myocardium in vivo.