Giovanni Di Leo1, Alexis Malavazos, Francesco Secchi, Calin Coman, Lelio Morricone, Massimiliano Marco Corsi, Gianluca Iacobellis2, Francesco Sardanelli1
1Unit of Radiology, Universit degli Studi di Milano, IRCCS Policlinico San Donato, San Donato Milanese, Milan, Italy; 2McMaster University
We assessed whether the epicardial adipose tissue (EAT) thickness is associated to the septal myocardial fat (SMF). Ten obese volunteers underwent echocardiographic EAT thickness measurement, 1.5-T 1H-MRS for SMF quantification (water reference) and MRI for EAT volume estimation. Intra- and interobserver reproducibility was excellent. SMF was 1-9%, EAT volume was 5-43 mL and EAT thickness was 3-11 mm. SMF showed a high correlation with EAT thickness, EAT volume, left ventricle mass and waist circumference. In multivariate regression, the EAT thickness was the only significant covariate of the SMF. We can speculate that EAT accumulation could reflect SMF in obese individuals.