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Abstract #1410

3D Non-Contrast-Enhanced MRA Using Flow-Sensitive Dephasing (FSD) Prepared Balanced SSFP: Identification of the Optimal First-Order Gradient Moment

Zhaoyang Fan1,2, Xiaoming Bi3, Xiangzhi Zhou1, Sven Zuehlsdorff3, Rohan Dharmakumar1, James Carr1, Debiao Li1,2

1Radiology, Northwestern University, Chicago, IL, United States; 2Biomedical Engineering, Northwestern University, Evanston, IL, United States; 3Cardiac MR R&D, Siemens Healthcare, Chicago, IL, United States


A noncontrast MRA technique using ECG-triggered 3D balanced SSFP with flow-sensitive dephasing (FSD) preparation has recently been validated in the distal lower extremities of healthy volunteers. The FSDs first-order gradient moment, m1, is shown to be the most important parameter to determine angiographic quality. This work developed a 2D m1-scout approach in which incremental m1 values were rapidly used to acquire 2D black-blood images and the optimal m1 value can be selected for 3D MRA. Its usefulness is validated on flow phantom and five healthy volunteer legs. This approach may also improve FSD-based vessel wall imaging.