Seongjin Choi1, Dustin Cunningham1,
Francisco Aguila1, John Corrigan2, Jennifer Bogner2,
Walter Mysiw2, Donald Chakeres1, Michael V. Knopp1,
As a part of optimization of diffusion tensor imaging (DTI) at 7T, we explored how voxel shape, voxel volume, and directional resolution affected FA measurement in normal aging brains at 7T and 3T. We observed statistically identical slopes while significantly different offset between the regression lines for FA along with age. In the study of SNR and FA over a range of reduction factors, we found that reduction factor affected standard deviation of measured FA values instead of FA itself.