Abstract #1690
An
Accelerated, Alternative Approach for Estimating Zero-Displacement
Probability in Hybrid Diffusion Imaging
A P. Hosseinbor1, J O. Fleming2,
Y-C Wu3, A A. Samsonov4, A L. Alexander
1Medical Physics, University of
Wisconsin-Madison, Madison, WI, United States; 2Neurology,
University of Wisconsin-Madison; 3Dartmouth College; 4Radiology,
University of Wisconsin-Madison
In
HYDI, Po is conventionally estimated by
using signal measurements in all shells (Poall), which requires long scan
time. However, the highest diffusion-weighting measurements are likely to
contribute most heavily to restricted diffusion (RD) signal. Thus, an
alternative, faster approach for characterizing RD would be to use signal
measurements only in outermost shell (Poouter). In this work, we compare both
Poall and Poouter approaches in NAWM from MS patients and WM in a control
group. We show that both approaches yield similar statistical properties for
characterizing RD, which suggests Poouter is both adequate and faster than
using full q-space measurements.
