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Abstract #1776

Measurement of Arterial Blood Velocity Distribution in the Human Brain Using Velocity Selective ASL

David Dawei Ding1, Jia Guo2, Eric C. Wong3,4

1School of Medicine, University of California - San Diego, La Jolla, CA, United States; 2Department of Bioengineering, University of California - San Diego, La Jolla, CA, United States; 3Department of Radiology, University of California - San Diego, La Jolla, CA; 4Department of Psychiatry, University of California - San Diego, La Jolla , CA, United States


This study measures the distribution of brain arterial blood velocity. Five subjects were scanned using velocity selective ASL. The velocity cut off of the image acquisition was held constant at 2cm/sec while the velocity cut off of the tag was 2, 4, 8, 16, 32, and 64cm/sec. The arterial blood fraction in each velocity bin was calculated, and showed that 60% of the blood flow is below 32cm/sec, with about 10% above 64 cm/sec. This data may help to optimize the design of velocity selective inversion pulses, and may be useful in the study of cerebral vascular physiology.