In Vivo 3D Imaging of Human Lateral Geniculate Nucleus Using Optimized Inversion Recovery Sequence at 3T and 7T

Chan Hong Moon¹, Jung-Hwan Kim¹, JinHong Wang¹, Kyongtae Ty Bae¹

We demonstrated excellent tissue contrast of the lateral geniculate nucleus (LGN) with suppression of signals from the surrounding white matters, such as optic radiation using an (inversion-recovery) MPRAGE sequence with appropriate TI at 3T and 7T. The LGN was superiorly delineated with a high SNR at 7T, as compared to 3T. An imaging method that allows for accurate and reliable volume measurement of LGN is essential for the investigation of the association between LGN atrophy in vivo and neurodegenerative glaucoma.