Mustafa Okan Irfanoglu1, Raghu Machiraju1, Michael V. Knopp1, Steffen Sammet1
1Department of Radiology, The
Diffusion Tensor Imaging proved to be a useful modality for the diagnosis of Multiple Sclerosis. However, the quality of the DTI-derived scalar maps and tractography is directly dependent on experimental design. In clinical settings, scan time is a major constraint and not many diffusion weighted volumes can be acquired. In this work, we analyze the effects of gradient resolution on the appearance of multiple sclerosis regions. Results indicate that with increasing number of gradients, statistics based on lesion scalar map distributions becomes more stable and spending extra minutes might be beneficial if DTI is to be assessed for diagnosis.