Josephine Helen Naish1,2, Geoff J M Parker1,2
1Imaging Science and Biomedical
Engineering, School of Cancer and Imaging Sciences, University of Manchester,
Manchester, United Kingdom; 2Biomedical Imaging Institute,
University of Manchester, Manchester, United Kingdom
We
present a two-compartment model of pulmonary oxygen-enhanced MRI (OE-MRI)
based on known gas exchange processes in the lung. The model relates the rate
of change of oxygen partial pressure to physiological parameters describing
ventilation, perfusion and blood oxygen solubility and allows quantitative
V/Q maps to be extracted from OE-MRI data.