Janet
Friedrich1, Julien Rivoire1, Alexander Wiegbert Scholz2,
Maxim Terekhov1, Rainer Kbrich2, Lars Krenkel3,
Claus Wagner3, Laura Maria Schreiber1
1Section of Medical Physics, Department
of Diagnostic and Interventional Radiology, Johannes Gutenberg University
Medical Center, Mainz, Germany; 2Department of Anesthesiology,
Johannes Gutenberg University Medical Center, Mainz, Germany; 3German
Aerospace Center, Gttingen, Germany
To
detect convective gas flow inside the large airways during high frequency
oscillated ventilation (HFOV) the fluorinated contrast gas Heptafluoropropane
was used for 19F-MRI. In a first study the comparison between constant flow
measurements and Computational Fluid Dynamics (CFD) simulations provided a
good agreement. In a following experiment oscillated flow was applied to a
lung phantom consisting of ventilation bag and long pipe. The pressure wave
inside the pipe was explored point-by-point and corresponding velocities were
determined. With these experiments it could be shown for the first time that
flow measurement during HFOV using fluorinated contrast gas is feasible.