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Abstract #2645

Effect of Region of Interest Position on Liver Apparent Diffusion Coefficient.

Daniel Wilson1, J. Ashley Guthrie2, Janice Ward2

1Medical Physics, Leeds Teaching Hospitals NHS Trust, Leeds, West Yorkshire, United Kingdom; 2Radiology, Leeds Teaching Hospitals NHS Trust, Leeds, West Yorkshire, United Kingdom


The liver ADC was measured in 3 different positions in the liver in 33 subjects. The mean ADC was signficantly different between the 3 different positions. This is attributed to the presence of noise in the middle of the liver and artefactual signal loss at high b-values at superior positions in the left lobe. Care must be taken when measuring ADC in the liver.