Yousef Mazaheri1, Daniel B. Rowe2, Jingbo Zhang3, Hedvig Hricak3, Jason A. Koutcher1
1Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States; 2Mathematics, Statistics, and Computer Science, Marquette University, Milwaukee, WI, United States; 3Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, United States
A stretched exponential model is presented to describe intravoxel incoherent motion (IVIM) signal. Simulations results show that the distributed diffusion coefficient and is a dimensionless stretching parameter have tolerable CV (<15% at 5% noise) and bias (absolute bias< 11% at 5% noise). In vivo renal data suggests that the stretched exponential model has potential to describe the pseudo-diffusion behavior at low b-values.