Martin D. Pickles1, Sue Booth2,
Lindsay W. Turnbull1
1Centre for MR Investigations,
University of Hull, Hull, East Yorkshire, United Kingdom; 2Institue
of Oncology, St James' Hospital, Leeds, West Yorkshire, United Kingdom
Chemoradiotherapy
in combination with brachytherapy has become the standard treatment for
advanced cervical carcinomas. Although the intent of the treatment is
curative a significant number of patients do not survive beyond 5 years. Consequently, biomarkers of reduced
survival intervals are currently being sought. The aim of this work was to
determine if any of the studied MR derived parameters were associated with
longer disease free and/or overall survival. This study demonstrated that for
this cohort the MR derived stage (FIGO or TNM) based on morphological
assessment of the disease present provided the most significant association
with survival intervals.