Mark Stephen Dobbs1,2, Neil Woodhouse3, Geoff J.M Parker1,2, Josephine H. Naish1,2
1Imaging Science and Biomedical Engineering, The University of Manchester, Manchester, Greater Manchester, United Kingdom; 2The University of Manchester Biomedical Imaging Institute, Manchester, Greater Manchester, United Kingdom; 3AstraZeneca, Manchester, Greater Manchester, United Kingdom
ASL has been applied extensively in the brain, but there has been increasing interest in applying ASL to the kidneys, particularly as a result of concerns over the link between contrast agents and NSF. Currently, most human renal-ASL has been performed using a single inversion time, and applying a simple model for quantification. In this abstract we aim to demonstrate the feasibility of applying the Buxton model, at 3T, using a STAR based labelling technique and a free breathing approach. Here, we demonstrate the practicality of fitting for arrival time, producing high quality parametric output.