Tatsuro Tsuchida1, Miwa Morikawa2,
Yukihiro Umeda2, Masato Sasaki3, Tomohito Kamibayashi1,
Hirohiko Kimura1
1Dept. of Radiology, University of
Fukui, Fukui, Japan; 2Dept. of Respiratory Medicine, University of
Fukui, Fukui, Japan; 3Dept. of Thoracic Surgery, University of
Fukui, Fukui, Japan
The
purpose of this study was to examine the utility of DWI-MRI for the
assessment of early response to chemotherapy in patients with advanced lung
cancer by comparing FDG-PET. Twenty-two lung cancer patients received MRI,
FDG-PET, and CT examination before and after 1 cycle of chemotherapy. Progression-free survival (PSF) between
responder and non-responder against chemotherapy was compared by means of %
change of ADC and SUV. Both index
indicated that responder demonstrated significant longer PSF and DWI-MRI will
be a promising tool for the assessment of the early response to chemotherapy.