William M. Spees1, Tsang-Wei Tu1, Sheng-Kwei Song1, Joel Garbow1
1Biomedical MR Laboratory, Washington University School of Medicine, St. Louis, MO, United States
Side-lobe spatial-spectral excitation and frequency-selective saturation with a binomial-series RF pulse scheme were evaluated for application at high field. Both methods yield separate water- or lipid-selective images in a single acquisition. In most circumstances, the performance of the binomial saturation approach proves to be more robust. A strategy is described for overcoming unwanted artifacts arising from magnetic susceptibility mismatch in small-animal imaging.