Aziz Hatim Poonawalla1, Ann Shimakawa2, Huanzhou Yu2, Charles McKenzie3, Jean Brittain2, Scott Reeder1,4
1Radiology, University of Wisconsin, Madison, WI, United States; 2GE Healthcare, Waukesha, WI, United States; 3Medical Biophysics, University of Western Ontario, London, Ontario, Canada; 4Medical Physics, University of Wisconsin, Madison, WI, United States
We have demonstrated the capability to acquire high-spatial resolution 3D volumetric images of the entire abdomen and pelvis, using a highly-accelerated chemical-shift-based water-fat separation technique and a 32-channel coil at 3.0T. The high-quality fat and fat-fraction images obtained by this technique provide unprecedented visualization and delineation of the adipose depot boundaries, with sufficient spatial resolution to allow 3D reformatting for optimal segmentation. This new technique will greatly facilitate rapid quantitative assessment of visceral adipose tissue volume, VAT/SCAT ratio, and total adipose volume within a single-breath-hold acquisition without the need for ionizing radiation.