Wenbo Wei1,
Guang Jia1, Steffen Sammet1, Peter Wassenaar1,
Jinyuan Zhou2, Michael Knopp1
1Department of Radiology, The Ohio
State University, Columbus, OH, United States; 2Department of
Radiology, Johns Hopkins University, Baltimor, MD, United States
In
this study, dual echo B0 mapping was used in Amide Proton Transfer
(APT) imaging for correcting B0 inhomogeneity with fewer data
points which will lead to approximately one third of the current scan time
and thus higher resolution. CEST spectrum, MTRasym curve and MTRasym
(3.5ppm) encoded color maps of the proposed APT method were compared to a conventional
method. The proposed method offers a more accurate MTR asym curve
shape and a better determination of the water resonance frequency which
allows a better MTRasym calculation.