Frank Q. Ye1, Charles C. Zhu1, Ning Liu2, Janita N. Turchi3, David A. Leopold1,3
1Neurophysiology Imaging Facility, National Institute of Mental Health, NIH, Bethesda, MD, United States; 2Laboratory of Brain and Cognition, National Institute of Mental Health, NIH; 3Laboratory of Neuropsychology, National Institute of Mental Health, NIH, Bethesda, MD, United States
High resolution, high contrast MRI scans can be used in neurophysiology research on nonhuman primates to plan invasive procedures that target deep brain structures. With procedures involving chronic, plastic head implants, susceptibility artifacts may severely distort the measurement of the projected entry trajectory. Geometric distortion correction based on field mapping is found both necessary and adequate to address this issue.