Heather Ting Ma1,2, Jing Yuan1, David K. Yeung1, Yi-Xiang Wang1, James Francis Griffith1
1Department of Diagnostic Radiology and Organ Imaging, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong; 2Electronic and Information Engineering Department, Harbin Institute of Technology Shenzhen Graduate Shool, Shenzhen, China
Varied bone marrow perfusion function in some bone diseases has been identified by dynamic contrast enhancement (DCE) MRI. This pilot study explored a non-invasive and quantitative method, combining kinetic model and arterial spine labeling (ASL) technique, to study bone marrow perfusion at lumbar spine. A turbo field echo (TFE) acquisition with STAR labeling (STAR-TFE) was developed for better imaging compared to STAR-EPI. A kinetic model was applied on the ASL signal to provide a quantitative measure of perfusion function. The result shows that ASL combined with kinetic modeling is promising for quantitative study the perfusion in bone marrow.