James F. Griffith1, David K. Yeung1, Jason SC Leung2, Timothy C. Kwok3, Ping C. Leung2
1Diagnostic Radiology and Organ Imaging, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong; 2Community & Family Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong; 3Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Shatin, Hong Kong
It would be useful to have a reliable means of predicting bone loss. As reduced bone perfusion and increased marrow fat content are associated with osteoporosis, this longitudinal study was undertaken to determine how well MR perfusion indices and marrow fat content at baseline could predict bone loss. It showed that reduced bone perfusion indices or increased marrow fat content at baseline is associated with increased bone loss over the ensuring four years with a predictive capacity comparable to traditional risk factors. MR-based indices also reliably distinguished future fast from slow bone losers. MRI has potential in predicting bone loss.