Single Shot, Chemical Shift Specific Imaging Methods for Hyperpolarized Carbon-13 Studies at 14T

Subramaniam Sukumar¹, Peder E.Z. Larson¹, Kayvan R. Keshari¹, John Kurhanewicz¹, Daniel B. Vigneron¹

Single shot, chemical shift specific, images are demonstrated using EPI and spiral acquisition techniques at 14T. These methods address some of the problems encountered with hyperpolarized 13C MRSI at high fields related to wide spectral dispersion. Spectral-spatial pulses are designed to selectively excite only the resonances of interest. The fast, single shot acquisition methods provide high temporal resolution on the order of 50-200msec and will be applicable to time course studies involving hyperpolarized 13C.