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Abstract #3327

Quantitative Lithium Spectroscopy in the Normal Human Brain on a 3T Clinical Scanner

Fiona Smith1, David Cousins2, Peter E. Thelwall1, I Nicol Ferrier2, Andrew M. Blamire1

1Newcastle MR Centre & Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; 2Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, United Kingdom


A quantitative protocol for localised 7Li of the human brain at 3T was developed. T1 relaxation of Li in healthy human brain was measured to be 2.00.4s. Brain Li concentration was measured to be 70% of plasma concentration.