Christian Labadie1,2, Stefan Hetzer1, Toralf Mildner1, Diana R. Amariei3, Monique Frcon4, Harald E. Mller1,2
1Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany; 2Faculty of Physics and Earth Science, University of Leipzig, Germany; 3Servei de Ressonncia Magntica Nuclear, Universitat Autnoma de Barcelona, Spain; 4Laboratoire de Spectromtrie Ionique et Molculaire, Universit Claude Bernard Lyon 1, France
A novel MRSI sequence, based on a double-shot echo planar spectroscopic readout, offers a full k-space sampling despite the limitation imposed by the spectral dwell-time of proton spectroscopy at 3 Tesla. In 61 sec, a spectroscopic image was acquired with a 12 x 12 matrix, TE of 33 ms, voxels of 4.91 mL and 16 steps EXOR phase cycling. The quantitation of the voxel spectra significantly determined NAA, creatine, choline and myo-inositol. A longer acquisition of 3 min 44 sec further permits to detect glutamine and glutamate.