Tun Jao1,2, Ya-Chih Yu1, I-Ning
Tang1, Chang-Wei Wu1, Jiann-Shing Jeng3,
Jyh-Horng Chen1
1MRI/MRS Lab, NTU, Taiwan, Taipei,
Taiwan; 2Department of Neurology, National Taiwan University
Hospital, Taipei, Taiwan; 3National Taiwan University Hospital,
Stroke Center and Department of Neurology, Taipei, Taiwan
In
this study, we deprive subjects from light and aim to investigate possible
fluctuations of DMN under visual deprivation. 10 healthy subjects underwent 4
resting-state scans: 1) eyes-closed in dark, 2) eyes-open in dark, 3)
eyes-closed in light, and 4) eyes-open in light. PCC was chose as the seed to
generate PCC-FC map. FC between PCC and PCu, thalamus, and prefrontal cortex
fluctuated significantly but incongruently. Besides the effect of
physiological conditions, DMN also showed changes upon light. To sum up, DMN
fluctuates incongruently across different situations. Both intrinsic
physiological activities and external environments contribute to these
changes.