Sheeba Arnold1, Susan Whitfield-Gabrieli2, Steven Shannon1, John Gabrieli2, Christina Triantafyllou1,3
1A.A. Martinos Imaging Center, McGovern Institute for Brain Research, MIT, Cambridge, MA, United States; 2Department of Brain and Cognitive Sciences, MIT, Cambridge, MA, United States; 3A.A. Martinos Center for Biomedical Imaging, Department of Radiology, MGH, Charlestown, MA, United States
BOLD activations cannot be located precisely with fMRI at low-resolutions. Improved sensitivity of 32-channel coil with high-resolution has been reported, but is yet to be demonstrated using fMRI at 3T. We used the n-back task to evaluate if this combination would identify the working memory (WM) network. 12- and 32-channel data at low- and high-resolutions were acquired in 18 subjects. Paired t-test revealed WM activation for high-resolution to be significantly more with 32-channel compared to 12-channel. When both coils are used at 3T, the increased SNR offered by 32-channel coil produces the greatest benefit for experiments in the high-resolution regime.