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Abstract #3646

Repair of Cardiac Damage Using Intrapericardial Drug Delivery by Means of MR-Trackable Alginate Beads

Yamin Yang1, Marco L.H. Gruwel2, Patricia Gervai3, Jiankang Sun3, Olga Jilkina1, Eugene Gussakovsky1, Valery Kupriyanov1

1Cardiac, NRC-CNRC Institute for Biodiagnostics, Winnipeg, MB, Canada; 2MRTechnology, NRC-CNRC Institute for Biodiagnostics, Winnipeg, MB, Canada; 3MRRD, NRC-CNRC Institute for Biodiagnostics, Winnipeg, MB, Canada


Re-establishment of a vascular network is an important step in the repair of damaged myocardium. For this purpose vascular growth factors were applied at the site of injury. To prolong action of these peptides, growth factors were incorporated in alginate beads. However, visualization of the beads is not an easy task.