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Abstract #3990

Multi-Center Reliability of Diffusion Tensor Imaging

Vincent Alfonso Magnotta1, Greg Bonett2, Bradley Bolster3, Bryon Mueller4, Kelvin Lim5, Susumu Mori6, Karl Helmer7, Jessica Turner8, Sara Reading9, Mark Lowe10, Elizabeth Aylward11, Laura Flashman1,2, Jane Paulsen1,3

1Radiology, The University of Iowa, Iowa City, IA, United States; 2Psychiatry, The University of Iowa, Iowa City, 52242, United States; 3Siemens Medical Solutions, Rochester, MN, United States; 4The University of Minnesota, Minneapolis, MN, United States; 5Psychiatry, The University of Minnesota, Minneapolis, MN, United States; 6Radiology, Johns Hopkins University, Baltimore, MD, United States; 7Radiology, Massachusetts General Hospital, Boston, MA, United States; 8Psychiatry and Human Behavior, University of California Irvine, Irvine, CA, United States; 9Psychiatry, Johns Hopkins University, Baltimore, MD, United States; 10Radiology, Cleveland Clinic Foundation, Cleveland, OH, United States; 11Seattle Children's Research Institute, Seattle, WA, United States; 12Psychiatry, Dartmouth, Hanover, NH, United States; 13Psychiatry, The University of Iowa, Iowa City, IA, United States


A multi-center study of diffusion tensor imaging was conducted to evaluate the coefficient of variation for sequence, site, and vendor. Small variations of less than 1% were found within a site that increased to 3% across vendors.