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Abstract #4020

Systematic Assessment of Effects of Noise and Resolution on Metrics of DTI Tractography

Virendra Radheshyam Mishra1,2, Xin Fan2, Hao Huang3,4

1Biomedical Engineering, The University of Texas at Arlington , Arlington, TX, United States; 2Advanced Imaging Research Center, The University of Texas Southwestern Medical Center , Dallas, TX, United States; 3Advanced Imaging Research Center, The University of Texas Southwestern Medical Center , Dallas, TX, United States; 4Department of Radiology, The University of Texas Southwestern Medical Center , Dallas, TX, United States


Fiber volume and fiber count are two important metrics derived from DTI tractography. However, no systematic description of the relationship between these two measures and noise or resolution has been reported so far. In this study, we measured fiber count and fiber volume of left cingulum with DTI datasets of different SNR and resolution. Our results indicate that resolution plays a more important role on both measures than SNR. With a normal range of SNR, both measures are almost constant for a normal resolution. Compared to fiber count, fiber volume is a more stable measure.