Edward S. Hui1,2, Steve H. Fung2,3,
Ed X. Wu1,4
1Laboratory of Biomedical Imaging and
Signal Processing, The University of Hong Kong, Hong Kong, Hong Kong; 2Department
of Radiology Research, The Methodist Hospital Research Institute, Houston,
TX, United States; 3Department of Radiology, Weill Medical College
of Cornell University, New York, United States; 4Department of
Electrical & Electronic Engineering, The University of Hong Kong, Hong
Kong, Hong Kong
Diffusion-weighted
(DW) signal attenuation depends on not only the diffusion gradient strength
but also the separation between the two diffusion gradients (i.e., diffusion
time Δ). In this study, the effect of Δ and diffusion weighting
factor b-value was examined and documented for conventional DTI by acquiring
DW signals with various b-values at different Δ from normal adult rat
brains in vivo.