Keigo Hikishima1,2, Masayuki Yamada3, Kanehiro Fujiyoshi4, Suketaka Momoshima5, Kenji Kawai1, Masaya Nakamura4, Norikazu Tamaoki1, Hideyuki Okano2
1Central Institute for Experimental Animals, Kasawaki, Kanagawa, Japan; 2Department of Physiology, Keio University; 3Fujita Health University; 4Department of Orthopaedic Surgery, Keio University; 5Department of Radiology, Keio University
The marmoset has a well-developed visual pathway; therefore, it has been used for studying the development of the optic chiasm. We performed high angular resolution diffusion imaging (HARDI) with high spatial resolution of the ex vivo optic chiasm in order to resolve the crossing pathways. We succeeded in visualizing the precise fiber structure in the optic chiasm with semidecussation, therefore ex vivo HARDI will be powerful tool for studying the neuroanatomic features of the optic chiasm.