Jia Guo1, Eric C. Wong2
1Department of Bioengineering, University of California San Diego, La Jolla, CA, United States; 2Department of Radiology and Psychiatry, University of California San Diego, La Jolla, CA, United States
We introduced a new method to image oxygen extraction fraction noninvasively using velocity selective excitation with arterial nulling (VSEAN). Compared to the QUIXOTIC method, VSEAN has following advantages: 1) higher SNR due to more relaxed venous blood; 2) no subtraction gives higher time efficiency; 3) insensitive to physiological noise; 4) a T2 map is generated every TR from multi-echo acquisition. Sequence design details were discussed and results from a human subject were presented.