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Abstract #4064

Minimizing Acquisition Time for Quantification of Regional Cerebral Blood Flow (RCBF) and Arterial Transit Time (ATT) Using Pseudo-Continuous ASL at 3.0T

Yasuhiro Fujiwara1, Hirohiko Kimura2, Tsuyoshi Matsuda3, Tomokazu Ishida1, Kyouji Higashimura1

1Radiological Center, University of Fukui Hospital, Fukui, Japan; 2Radiology, University of Fukui, Fukui, Japan; 3GE Healthcare Japan, Tokyo, Japan


The purpose of this study was to evaluate the effect of the number of post labeling delay times and averages to reproduce and minimize acquisition time for precise rCBF quantification. As result of this study, When performing pCASL at post label delay of 0.5, 1.0, 1.5s, reproducible perfusion images were obtained with sufficient SNR in the condition of 12 averages. Using 3 time points protocol, scanning time can be minimized as short as 5 minutes.