Stephan Ulmer1, Gesa Hartwigsen2, Michael Helle1, Olav Jansen1, Maximillian Hubertus Mehdorn3, Arya Nabavi3
1Institute of Neuroradiology, University Hospital of Schleswig-Holstein, Kiel, Germany; 2Department of Neurology, University Hospital of Schleswig-Holstein, Kiel, Germany; 3Department of Neurosurgery, University Hospital of Schleswig-Holstein, Kiel, Germany
Dynamic susceptibility contrast MRI (DSC-MRI) was applied in a model with an air-fluid-level and in a flow phantom to assess possible artifacts of an intraoperative setting. In 6 patients with glioblastoma multiforme iDSC-MRI was performed. In both models there were only minor distortions. In 5 patients complete removal of the lesion was already achieved by the time of iDSC-MRI. In the remaining case tumor could be depicted that demonstrated identical perfusion ratio as in the preoperatively acquired scans. DSC-MRI is technically feasable intraoperatively and enables a differentiation of residual tumor from contrast-enhancement caused by surgical manipulation in these intraoperative MRIs.