David Arthur Woodrum1, Lance Mynderse2, Akira Kawashima1, Krzysztof Gorny1, Thomas Atwell1, Fred Mcphail2, Bradley Bolster3, Wesley Gilson3, Kimberly Amrami1, Haraldur Bjarnason1, Matthew Callstrom1
1Radiology, Mayo Clinic, Rochester, MN, United States; 2Urology, Mayo Clinic, Rochester, MN, United States; 3Siemens Medical Solutions, Inc.
Prostate cancer recurrence after definitive therapy can be as high as 25% after 15 years. Detection of these recurrences can be achieved using serial PSA coupled with dynamic contrast enhanced (DCE) MRI. Our hypothesis is MR-guided cryoablation can be used in the setting of prostate bed PAC recurrence to perform a precise image-guided focal ablation. Two patients with prior RRP and dynamic contrast enhancement(DCE) MRI abnormalities in the prostate bed were treated using MR-guided cryoablation. Both patients with recurrent prostate cancer in the prostate bed were successfully treated with MR-guided cryoablation. Immediate post-ablation DCE MRI demonstrated no definite residual tumor.