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Abstract #4224

19F MRI of Trifluoroacetic Acid Encapsulated Into Liposomes

Mirko Meiner1, Germaine Loredana Truisi2, Constantin von zur Mhlen2, Gerhard Ptz3, Dominik von Elverfeldt1

1Dept. of Diagnostic Radiology / Medical Physics, University Hospital Freiburg, Freiburg, Germany; 2Dept. of Cardiology and Angiology, University Hospital Freiburg, Freiburg, Germany; 3Dept. of Clinical Chemistry, University Hospital Freiburg, Freiburg, Germany


Gd-liposomes had been synthesized with a novel dual asymmetric centrifugation technique. Using MRI we examined the in vitro T1-Relaxivity at 9.4 T and could show the influence of the internal Gd-concentration on the in vitro relaxivity of liposome encapsulated Gd-DTPA.