Zhengguang Chen1, Lifeng Lao2, Jianxiong Shen3, Xiaozhen Li4
1Department of Radiology, First Hospital of Tsinghua University, Beijing, China; 2Department of Orthopaedic, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China; 3Department of Orthopedics, Peking Union Medical College Hospital, Peking Union Medical College, Beijing, China; 4Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College, Beijing, China
Adolescent Idiopathic Scoliosis (AIS) is defined as a lateral spinal curvature greater than 10 accompanied by vertebral rotation and has no clear underlying causes. Traditionally AIS was evaluated using standing radiographs of the full spine to assess lateral curvature with the Cobb method, but it is on 2D coronal plane-only evaluating system, ignoring the 3D nature of AIS. MRI and computer-generated 3D images is a noninvasive procedure which could be used to assess the functional morphology in spine. To validate the hypothesis of disproportional growth between neural and skeletal system a MRI study was performed in 149 AIS patients and 41 age-matched controls.