Christian Langkammer1, Christian Enzinger1, Siegrid Fuchs1, Franz Fazekas1, Stefan Ropele1
1Department of Neurology, Medical University of Graz, Graz, Austria
Signal abnormalities in multiple sclerosis such as neocortical and juxtacortical lesions can be visualized best using a double inversion recovery (DIR) sequence. DIR sequences are based on T1 filtering and aim on suppressing signal from white matter and cerebrospinal fluid. We here investigated, whether the application of additional MT saturation pulses can further improve the contrast between cortex, white matter and embedded lesions. The new sequence was evaluated in the brain of healthy volunteers and multiple sclerosis patients.