Christopher Leslie Adamson1, Amanda Wood1,2, Jian Chen1, Sarah Barton1, David Reutens3, Mark Walterfang4,5
1Developmental and Functional Brain Imaging, Murdoch Childrens Research Institute, Melbourne, VIC, Australia; 2Department of Medicine, Southern Clinical School, Monash University, Melbourne, VIC, Australia; 3Centre for Advanced Imaging, University of Queensland, Brisbane, QLD, Australia; 4Neuropsychiatry Unit, Royal Melbourne Hospital, Melbourne, VIC, Australia; 5Melbourne Neuropsychiatry Centre, University of Melbourne, Melbourne, VIC, Australia
We present a method to generate thickness profiles of the corpus callosum from midsagittal slices of MR images. The method is mostly automated, robust and computationally efficient. We utilise the method to reveal morphological changes of the corpus callosum at different stages of schizophrenia.