Vitaliy L. Rayz1, Loic Boussel2, Liang Ge3, Joe R. Leach1, Alastair J. Martin1, Michael T. Lawton4, David Saloner1
1Radiology, University of California San Francisco, San Francisco, CA, United States; 2Creatis-LRMN (LB, PCD), Lyon, France; 3Surgery, University of California San Francisco; 4Neurological Surgery, University of California San Francisco
Thrombus deposition in cerebral aneurysms presents an increased risk of thrombo-embolism. The effect of increased flow residence time (RT) on thrombus deposition was investigated using a new numerical flow visualization technique. MR angiography and MR velocimetry data were used to construct patient-specific numerical models of the flow in three basilar aneurysms with known regions of thrombus deposition. The flow RT maps computed with CFD in the base-line geometries were compared with intra-aneurysmal regions that were observed to clot at the follow-up MRI studies. The results show that intra-aneurysmal regions with increased flow residence time are prone to thrombus deposition.