Samuel Lapere1, Evelien Carrette2,
Paul Boon2, Kristl Vonck2, Xavier De Tige3,
Eric Achten1, Karel Deblaere1
1Department of Radiology, Ghent
University Hospital, Ghent, Belgium; 2Reference Center for
Refractory Epilepsy, Department of Neurology, Ghent University Hospital; 3Laboratoire
de Cartographie Fonctionelle du Cerveau, ULB Erasmus Hospital Brussels,
Belgium
Patients
with refractory epilepsy in whom the epileptogenic zone cannot be precisely
identified are not likely to undergo resective surgery. This study aims to
assess the potential of surface coil imaging at 3T guided by
magnetoencephalography (MEG) to locate the epileptogenic zone. Fifteen
patients with dipole clustering on MEG (indicating the possible epileptogenic
zone) were scanned with a surface coil at 3T. MEG-guided surface coil imaging
at 3T showed an added value in the detection of lesions previously not
visible or missed on 3T MRI, and demonstrated an improved delineation and
electrophysiological validation of previously known lesions.