Marina Benito1, Alexia Rodrguez-Ruano2, Cristina Chavarrias1, Paula Montesinos1, Manuel Desco1
1Unidad de Medicina y Ciruga Experimental, Hospital General Universitario Gregorio Maran, Madrid, Spain; 2Unidad de Medicina y Ciruga Experimental , Hospital General Universitario Gregorio Maran, Madrid, Spain
SWI allows to delineate the cerebral veins in high quality, however during the MRI exam animals are anaesthetized. Anesthetics make vary the venous contrast depending on the deepness of anesthesia, but when using inhalated anesthesia the venous response on SWI also depends on the partial pressure of oxygen (pO2) in the supplied gas. This study investigates how the pressure of oxygen in the supplied gas affects the venous contrast in SWI in order to study the microvasculature of the rat brain.