Jesse L. Wei1,2, Kimiknu Mentore1,
Martin P. Smith1,2, Neil M. Rofsky1,2
1Radiology, Beth Israel Deaconess
Medical Center, Boston, MA, United States; 2Harvard Medical
School, Boston, MA, United States
Administration
of Gd-EOB-DTPA using the recommended dose for hepatobiliary imaging results
in an unfamiliar "washed out" appearance of the liver on dynamic
contrast enhanced (DCE) imaging. This likely results from increased
background hepatic enhancement due to early hepatobiliary uptake. Injection of a combination of Gd-EOB-DTPA
in conjunction with an extracellular contrast agent provides the 20-minute
delayed hepatobiliary phase, while preserving the familiar vascular contrast
and lesion conspicuity compared to background liver on DCE images.