Arnaud Comment1,2, Sami Jannin3, Jean-Nol Hyacinthe4, Pascal Miville3, Riddhiman Sarkar3, Puneet Ahuja3, Paul Romeo Vasos3, Xavier Montet4, Franois Lazeyras4, Jean-Paul Valle4, Joseph A. Konter5, Patrick Hautle5, Ben van den Brandt5, Jean-Philippe Ansermet2, Rolf Gruetter1,6, Geoffrey Bodenhausen3,7
1Laboratory for Functional and Metabolic Imaging, Ecole Polytechnique Fdrale de Lausanne, Lausanne, Switzerland; 2Institute of Condensed Matter Physics, Ecole Polytechnique Fdrale de Lausanne, Lausanne, Switzerland; 3Laboratory of Biomolecular Magnetic Resonance, Ecole Polytechnique Fdrale de Lausanne, Lausanne, Switzerland; 4Department of Radiology, Universit de Genve, Genve, Switzerland; 5Paul Scherrer Institute, Villigen, Switzerland; 6Departments of Radiology, Universits de Lausanne et Genve, Lausanne and Genve, Switzerland; 7Department of Chemistry, Ecole Normale Suprieure, Paris, France
A method to produce hyperpolarized gases by dynamic nuclear polarization and subsequent sublimation was designed. The method was illustrated by applications to 129Xe in xenon gas, leading to the enhancement of the nuclear magnetic resonance signal-to-noise by four orders of magnitude. The main advantage of this new hyperpolarization method lies in its ability to produce highly polarized gases with large throughputs, on the order of tens of several liters per hour.